This study provides valuable insights into the role of MATR3 in oocyte maturation and folliculogenesis, using conditional knockout mice and in vitro follicle culture systems to show that MATR3 is ...

Researchers boosted levels of a heart-healing hormone in mice and pigs with a single injection of a new, experimental form of self-amplifying RNA that prolonged hormone synthesis for many weeks. When ...

A bacterium from frog gut microbiota eliminated tumors in mice by selectively colonizing tumors and triggering both direct ...

“Insulin injections remain a daily burden for many patients,” said Shingo Ito, an associate professor at Kumamoto University ...

Current schizophrenia drugs can quiet hallucinations and delusions, but the cognitive symptoms (disorganized thinking, memory problems, executive dysfunction) stay untreated. Those are the ones that ...

The powerful gene-editing technique CRISPR–Cas9 might offer a way to make safer, more effective cancer-fighting immune cells engineered inside the human body, a mouse study has found. Cancer-fighting ...

Background Neutrophils guarantee a prompt and robust host response to pathogens. Yet, overshooting neutrophil activation ...

For over a century, scientists have chased the dream of insulin pills, but the digestive system kept destroying the drug before it could work—forcing millions of patients to rely on daily injections.

BACKGROUND: Despite antiplatelet therapy, some patients remain at high ischemic risk because of drug nonresponsiveness or high residual platelet reactivity). We aimed to target an orphan platelet GPCR ...

Researchers at Johns Hopkins University and the University of Maryland School of Pharmacy have developed a set of novel, ...

Combination therapy led to complete remission in more than 50% of mice with different tumor types, many of which were resistant to ICB therapy alone.