Integration of single-cell multiomics data allows a more precise identification of rare cell types and states

Researchers at the Josep Carreras Leukaemia Research Institute have demonstrated that combining data from different origins ...
Nature

Various cell types in tissues cooperate in networks that are disrupted in disease

Gene expression reveals that different types of human cell can work as a unit. These cellular modules, found in several tissues, change during disease. However, suitable computational methods are ...
Science Daily

Massive single-cell atlas across human tissues highlights cell types where disease genes are active

Genetic studies have revealed many genes linked to both common and rare disease, but to understand how those genes bring about disease and use those insights to help develop therapies, scientists need ...
Science Daily

Seasonal and circadian genetic variation charted across the human body

A study expands the list of known genes with circadian variation and provides the first comprehensive list of genes with seasonal variation in each tissue. Tissues in the thoracic cavity, such as the ...