Oestrogen-induced DNA damage drives genomic instability in BRCA1 mutation cells, with dietary compounds showing protective potential.

Findings may support development of more refined personalized breast cancer risk prediction models for BRCA1 pathogenic ...

Damaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast ...

Damaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast ...

In a study that involved more than 31,000 women who are carriers of disease-associated mutations in the BRCA1 or BRCA2 genes, researchers identified mutations that were associated with significantly ...

Genetic mutations found in the body’s immune response are “significantly associated” with earlier breast cancer onset among ...

In a study of more than 31,000 women who have inherited mutations in BRCA1 or BRCA2 genes, researchers determined that the level of risk for breast and ovarian cancer is dependent on the type of ...

A clustered family history of breast, ovarian, and colon cancers appropriately triggered germline testing, with BRCA1 mutation status informing individualized risk stratification and counseling.

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its ...

People inherit two copies of each gene — one from each parent — an evolutionary fail-safe to ensure survival even when one of them doesn’t function. Likely not, according to the findings of a new ...

We talked to experts about new research connecting mutations in BRCA genes to other forms of cancer besides breast and ovarian. If you typically think of BRCA gene mutations along with certain breast ...

ComingSoon can exclusively reveal the trailer for Love, Danielle. Love, Danielle is a new dramedy movie about a woman who tests positive for a BRCA1 gene mutation, which then puts her at high risk of ...